Research

Access the database of our experimental results

Here yo may access the search engine to look for genes of your interest within our experimental results:
Data set 1 - Time-course analysis of gene expression in human breast cancer ZR-75.1 cells stimulated with 17beta-estradiol (Cicatiello et al., 2004).
Data set 2 - Genomic action of antiestrogens in ZR-75.1 cells (Scafoglio et al., 2006).
Data set 3 - Time-course analysis of gene expression in human breast cancer ZR-75.1 cells stimulated with 17beta-estradiol (NEW - Illumina Whole Genome Human-6 BeadChips)
Data set 4 - Time-course analysis of gene expression in human breast cancer MCF-7 cells stimulated with 17beta-estradiol (NEW - Illumina Whole Genome Human-6 BeadChips)

Additional data

Tables and Figures from our publications will be available here (we are waiting for the Publisher's permission).

References:

  • Scafoglio C, Ambrosino C, Cicatiello L, Altucci L, Ardovino M, Bontempo P, Medici N, Molinari AM, Nebbioso A, Facchiano A, Calogero RA, Elkon R, Menini N, Ponzone R, Biglia N, Sismondi P, De Bortoli M, and Weisz A (2006)
    Comparative gene expression profiling reveals partially overlapping but distinct genomic actions of different antiestrogens in human breast cancer cells.
    J Cellular Biochem, accepted/in press.     PMID: 16514628

  • Ambrosino C, Cicatiello L, Scafoglio C, Altucci L and Weisz A. (2005)
    A Combinatorial Approach to Gene Expression Analysis: DNA Microarrays. In: Combinatorial Chemistry and Technology, Principles, Methods and Applications, 2nd ed. (Eds. Miertus, S., Fassina, G.), Marcel Dekker, New York, pp. 539-565. [Full text]

  • Nebbioso, A., Clarke, N., Volz, E., Germain, E., Ambrosino, C., Bontempo, P., Alvarez, R., Schiavone, E.M., Ferrara, F., Bresciani, F., Weisz, A., de Lera, A.R., Gronemeyer, H. & Altucci, L. (2005)
    Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukaemia cells.
    Nat. Medicine 11: 77-84. PMID: 15619633

  • Scafoglio, C. & Weisz, A. (2005)
    Review of: The Inhibitor of Cyclin-Dependent Kinase 4a/Alternative Reading Frame (INK4a/ARF) Locus Encoded Proteins p16INK4a and p19ARF Repress Cyclin D1 Transcription through Distinct cis Elements.
    Breast Cancer Online (http://www.bco.org) 8(2). [Full text]

  • A. Weisz (2005)
    New insights on estrogen action from gene expression profiling. In: Signal Transduction and Neoplastic Transformation in Endocrine Systems: Molecular mechanisms and clinical aspects. (Eds. Vecchio, G. et al.) Accademia dei Lincei Press, Roma, pp.143-153. [Full text]

  • L. Cicatiello, C. Scafoglio, L. Altucci, M. Cancemi, G. Natoli, A. Facchiano, G. Iazzetti, R. Calogero, N. Biglia, M. De Bortoli, C. Sfiligoi, P. Sismondi, F. Bresciani and A. Weisz (2004)
    A genomic view of estrogen actions in human breast cancer cells by expression profiling of the hormone responsive transcriptome
    J. Mol. Endocrinology, 32, 719-775. PMID:     15171711

  • Weisz A, Basile W, Scafoglio C, Altucci L, Bresciani F, Facchiano A, Sismondi P, Cicatiello L, De Bortoli M. (2004)
    Molecular identification of ER -positive breast cancer cells by the expression profile of an intrinsic set of estrogen regulated genes.
    Journal of Cellular Physiology, 200: 440-450. PMID: 15254972

  • Mutarelli, M., Basile, W., Cicatiello, L., Scafoglio, C., Colonna, G., Weisz, A., Facchiano, A. (2004)
    Comparative analysis with three different microarray platforms of the estrogen-responsive transcriptome from breast cancer cells.
    Proceedings of BITS 2004 (Bioinformatics Italian Society Meeting 2004).
    Abstract

  • Cordero, F., Lazzarato, F., De Bortoli, M., Weisz, A., Cicatiello, L., Scafoglio, C., Basile, W. & Calogero, R. (2004)
    Putative Estrogen-Responsive Genes database (PERG).
    Proceedings of BITS 2004 (Bioinformatics Italian Society Meeting 2004).
    Abstract

  • Sorbello V, Fuso L, Sfiligoi C, Scafoglio C, Ponzone R, Biglia N, Weisz A, Sismondi P, De Bortoli M. (2003)
    Quantitative real-time RT-PCR analysis of eight novel estrogen-regulated genes in breast cancer.
    Int J Biol Markers. 2003 Apr-Jun;18(2):123-9. PMID: 12841681

  • Cicatiello, L., Scafoglio, C., Facchiano, A., Mutarelli, M., Weisz, A. (2003)
    Analysis of the estrogen-responsive transcriptome from breast cancer cells: a comparative analysis with three different microarray platforms.
    Proceedings of the NETTAB 2003 Workshop: 'Bioinformatics for the management, analysis and interpretation of microarray data' (Eds. Marabotti, A., A. Facchiano, P. Romano), pp. 73-77, 2003 [Full text]

  • M. Mutarelli, G. Colonna, A. Facchiano (2003)
    A bioinformatic workbech for the analysis of microarray data based on open source software and public databases. [Full text]
    Proceedings of the NETTAB 2003 Workshop: 'Bioinformatics for the management, analysis and interpretation of microarray data' (Eds. Marabotti, A., A. Facchiano, P. Romano), pp. 73-77, 2003

  • L. Cicatiello, A. Facchiano, R. Calogero, M. De Bortoli, F. Bresciani, and A. Weisz (2001)
    Gene expression monitoring in hormone-responsive human breast cancer cells during estrogen-induced cell cycle progression.
    Nature Genetics "Oncogenomics Conference - Dissecting cancer through genome research".
    January 25-27, 2001, Tucson, Arizona, USA.
    Abstract

  • Facchiano, A., Weisz, A. (2001)
    Internet tools for the analysis of gene expression by data bases integration.
    Proceedings of the NETTAB 2001 Workshop: 'CORBA and XML: Toward a bioinformatics integrated network environment' (Eds. Iannotta, B., F. Malusa, D. Marra, P. Romano), pp. 99-101, 2001. [Full text]